Dr. Matthew Opoku Prempeh (born 23 May 1968) is a medical doctor and a politician. He is a member of the New Patriotic Party serving as a Member of Parliament for Manhyia South Constituency in the Ashanti Region of Ghana. He is popularly known as Napo. He is currently the Minister of Energy.
He was first elected to Parliament in 2008. In 2016, he was re-elected with 87.17% of the votes cast in the district.
Dr. Prempeh studied Human Biology and Medicine at Kwame Nkrumah University of Science and Technology, later continuing post-graduate studies at the Netherlands Institute of Health Sciences and the Kennedy School of Government at Harvard University.
Prior to parliament, he served as CEO of Keyedmap Security Services Limited from 2004 to 2009 and as a member of the Royal College of Physicians and Surgeons of the United Kingdom from 1999 to 2003.
He identifies as a Christian and is a nephew of the former Ghanaian president, John Kufuor. He is divorced.
He was appointed by President Nana Akufo-Addo on 10 January 2017 to serve as Minister for Education of Ghana. He served in that role for 4 years till 6 January 2021 when the tenure of office of the president and his ministers ended.